Natural History of Chronic Hepatitis B REVEALed | reveal hbv
REVEAL-HBVCohortStudyIn1991–1992,acommunity-basedcohortstudyonvirus-relatedcancerswascarriedoutinseventownshipsinTaiwan.Atotalof89293maleandfemaleresidentsaged30to65yearswereinvitedtoparticipate,and23820wereenrolledwithaninformedconsent.Theyagreedtoparticipateinquestionnaireinterview,healthexaminationandbloodcollectionforserologicalandbiochemicalassaysatstudyentryandregularfollow-up.Theyalsogavetheirconsentforconfirmingtheirhealthandvitalstatusthroughmedicalrecordreviewandcomputerizeddatalin...
REVEAL-HBV Cohort StudyIn 1991–1992, a community-based cohort study on virus-related cancers was carried out in seven townships in Taiwan. A total of 89 293 male and female residents aged 30 to 65 years were invited to participate, and 23 820 were enrolled with an informed consent. They agreed to participate in questionnaire interview, health examination and blood collection for serological and biochemical assays at study entry and regular follow-up. They also gave their consent for confirming their health and vital status through medical record review and computerized data linkage with national health insurance, cancer registry and death certification profiles. The health examination at study entry included abdominal ultrasonography and serological tests of HBsAg, HBeAg, antibodies against hepatitis C virus (an...