Endometrioid carcinoma of the uterine corpus | uterine corpus
Thisreviewconsidersthepathologicfeaturesofendometrioidcarcinomaoftheuterinecorpus,whichaccountsforapproximately80%ofendometrialadenocarcinomas,withanemphasisonitshistologicfeatures,recentadvances,andproblematicaspects.Inadditiontotypicalendometrioidcarcinoma,thevariantsofendometrioidcarcinomacoveredincludesecretorycarcinoma,villoglandularendometrioidcarcinoma,endometrioidcarcinomawithsmallnonvillouspapillae,endometrioidcarcinomaswithmicroglandularandsertoliformpatterns,andendometrioidcarcino...
This review considers the pathologic features of endometrioid carcinoma of the uterine corpus, which accounts for approximately 80% of endometrial adenocarcinomas, with an emphasis on its histologic features, recent advances, and problematic aspects. In addition to typical endometrioid carcinoma, the variants of endometrioid carcinoma covered include secretory carcinoma, villoglandular endometrioid carcinoma, endometrioid carcinoma with small nonvillous papillae, endometrioid carcinomas with microglandular and sertoliform patterns, and endometrioid carcinomas with metaplastic changes. These changes include a variety of different appearances of squamous epithelia (ranging from mature and keratinizing to immature with only subtle evidence of a squamous nature), clear cells, surface changes resembling syncytial metaplasia or microglandular hyperplasia, ciliated cells, oxyphilic cells, and spindled epithelial cells (sarcomatoid carc...