Uterine Corpus Tumours | uterine corpus
Chapter1-HistopathologyofGynaecologicalCancersIntheuterinecorpustherearethreemajorcategoriesofcancer:(1)epithelial,(2)mesenchymaland(3)mixedepithelialandmesenchymal.Uterineleiomyosarcoma(LMS)isthemostcommontypeofmesenchymalmalignanttumour;microscopicfeaturesofLMSincludecytologicalatypia,mitoticactivityandnecrosis.TheyareaggressivealsowhenStage1.EndometrialstromalsarcomaislessfrequentthanLMS.Mostarelow-gradetumoursandthestageisprognosticallyrelevant;fewarehighgrade.Theyshowtypicalgeneticanoma...
Chapter 1 - Histopathology of Gynaecological CancersIn the uterine corpus there are three major categories of cancer: (1) epithelial, (2) mesenchymal and (3) mixed epithelial and mesenchymal.
Uterine leiomyosarcoma (LMS) is the most common type of mesenchymal malignant tumour; microscopic features of LMS include cytological atypia, mitotic activity and necrosis. They are aggressive also when Stage 1.
Endometrial stromal sarcoma is less frequent than LMS. Most are low-grade tumours and the stage is prognostically relevant; few are high grade. They show typical genetic anomalies.
FIGO staging of endometrial carcinoma: Stage I: limited to the corpus; Stage II: infiltration of the cervi...