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Bi-specificT-cellengagers(BiTEs)areaclassofartificialbispecificmonoclonalantibodiesthatareinvestigatedforuseasanti-cancerdrugs.,Bi-specificT-cellengagers(BiTEs)areaclassofartificialbispecificmonoclonalantibodiesthatareinvestigatedfortheuseasanti-cancerdrugs.Theydirecta ...
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Bi | bite antibody
Bi-specific T-cell engagers (BiTEs) are a class of artificial bispecific monoclonal antibodies that are investigated for use as anti-cancer drugs. Read More
Bi-specific T | bite antibody
Bi-specific T-cell engagers (BiTEs) are a class of artificial bispecific monoclonal antibodies that are investigated for the use as anti-cancer drugs. They direct a ... Read More
Bispecific T cell engager (BiTE®) antibody constructs can ... | bite antibody
由 SL Ross 著作 · 2017 · 被引用 68 次 — Targeting CD19 with blinatumomab, a CD19/CD3 bispecific antibody construct (BiTE®), or with chimeric antigen receptor T cells (CAR-T) has shown great promise ... Read More
Bispecific T cell engagers | bite antibody
由 Z Tian 著作 · 2021 · 被引用 86 次 — Different from natural antibodies, BiTEs can redirect T cells to specific tumor antigens and activate T cells directly. Natural antibodies are ... Read More
Bispecific T | bite antibody
由 Z Shah 著作 · 2019 · 被引用 2 次 — IntroductionBispecific T-cell engager (BiTE) antibodies represent a novel therapeutic option for patients with multiple myeloma (MM). Read More
BiTE – The Next Innovative Treatment in Lymphoma and ... | bite antibody
2019年9月13日 — BiTE is short for "bispecific T cell engager". BiTEs are antibodies with two arms. One arm of the drug attaches to a specific protein on the tumor ... Read More
BiTEs | bite antibody
由 C Allen 著作 · 2021 · 被引用 16 次 — Bispecific T cell engagers (BiTEs) were one of the first antibody-based leukemia therapies engineered, with the anti-CD3 × CD19 antibody ... Read More
BiTE® Molecule | bite antibody
A BiTE® antibody construct is a type of fusion protein that is designed to harness the power of the immune system to treat cancer. BiTE® molecules are deigned ... Read More
BiTE® Molecule | bite antibody
These bispecific molecules are created by linking the targeting regions of two antibodies. One arm of the molecule is engineered to bind with a protein found on ... Read More
BiTE免疫治療的進展及衍生/鄭吉元、陳宜正、蔡慈貞、張文震 | bite antibody
2022年6月30日 — 雙特異性T細胞銜接系統(bispecific T-cell engager,BiTE) 是一種雙特異性抗體,可以引導人體免疫細胞中的T細胞,主要是毒殺型T細胞去攻擊癌細胞,猶如 ... Read More
CARs versus BiTEs | bite antibody
由 CY Slaney 著作 · 2018 · 被引用 86 次 — A BiTE is a recombinant bispecific protein that has two linked scFvs from two different antibodies, one targeting a cell-surface molecule on T cells ... Read More
Efficacy and safety of bispecific T | bite antibody
由 J Yu 著作 · 2019 · 被引用 20 次 — Efficacy and safety of bispecific T-cell engager (BiTE) antibody blinatumomab for the treatment of relapsed/refractory acute lymphoblastic leukemia and ... Read More
The BiTE (bispecific T‐cell engager) platform | bite antibody
由 H Einsele 著作 · 2020 · 被引用 14 次 — BiTE molecules are antibody constructs with 2 binding domains: 1 recognizing tumor-expressed antigens (eg, BCMA, CD19, δ-like protein 3 ... Read More
The BiTE antibody principle. Generation of a BiTE antibody ... | bite antibody
Generation of a BiTE antibody from the variable domains of two distinct monoclonal antibodies is depicted on the left. The anti-CD3 specific single-chain antibody ( ... Read More
The landscape of bispecific T cell engager in cancer treatment | bite antibody
由 S Zhou 著作 · 2021 · 被引用 70 次 — BiTE is a bispecific antibody construct with a unique function, simultaneously binding an antigen on tumor cells and a surface molecule on T ... Read More
Therapeutic Bispecific T | bite antibody
由 M Fu 著作 · 2019 · 被引用 17 次 — Bispecific T-cell engager antibodies (BiTE) have been explored as a means to recruit cytolytic T cells to kill tumor cells. Read More
Utilizing the BiTE (bispecific T | bite antibody
由 J Stieglmaier 著作 · 2015 · 被引用 50 次 — BiTE antibody constructs (a registered trade mark of Amgen Inc.) are designed from monoclonal antibodies and have a unique mechanism of action, linking T-cells ... Read More
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